Genome-Wide Assessment for Improving Recruitment Processes in Military Environments: A Systematic Review of Attention Performance-Related Disorders

Document Type : Review

Authors

1 Research Center for Exercise Physiology, Lifestyle Research Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran

2 AJA University of Command and Staff, Tehran, Iran

Abstract

Background and Aim: Nowadays, genetic science is extensively utilized in the recruitment processes of advanced organizations to employ individuals with higher efficiency. However, genetic assessments are highly expensive, and the most appropriate genes for evaluation must be identified before their application. This study aims to identify the most suitable genes for evaluating attention performance to improve the recruitment process in military forces.
Methods: The search process was conducted without restrictions on sample size, country, language, or study design, focusing on the exposure factor and outcome. A systematic search, without time limits until March 1, 2024, was conducted in the Scopus, PubMed, and Web of Science databases. Using the PEOS framework, the population was defined as individuals with attention disorders and healthy individuals, exposure as specific alleles in the COMT, SLC6A3, and DRD4 genes, outcome as attention-related disorders, and study design as case-control studies.
Results: After a systematic search, 295 studies on the COMT gene, 181 studies on the SLC6A3 gene, and 349 studies on the DRD4 gene were obtained. After removing duplicate studies, 691 studies remained. Ultimately, after reviewing the existing studies, 19 studies on COMT, 25 studies on SLC6A3, and 24 studies on DRD4 were considered for discussion in this study.
Conclusion: Examining the SLC6A3 gene as part of the pre-recruitment assessment process in military organizations can be an effective approach to improving this process and facilitating the recruitment of more efficient individuals.

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