Effect of Green Tea Extract on Exercise-Induced Inflammatory Markers

Document Type : Original Research

Authors

1 Baqiyatallah University of Medical Sciences

2 Applied Virology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

Abstract

Background and Aim: Intensive resistance trainings cause the production of many free radicals and pre-inflammatory cytokines in athletes and military personnel. These factors may cause many complications for the athlete. In recent years, the use of anti-inflammatory compounds made of herbal extracts has been considered to reduce these inflammatory factors. The purpose of this study was to evaluate the effect of green tea extract on inflammatory cytokines caused by endurance trainings in athletes.
Methods: This study was conducted on 36 male athlete. Their individual characteristics including height, weight, body mass index were measured. Subjects (N=36) were randomly divided into three groups. The first group did their exercises without any supplement or medication. The green tea extract and the placebo were used along with the TRX training in group two and three respectively. Serum levels of IL-6 and TNF-α inflammatory factors were evaluated by ELISA method in all groups.
Results: Serum levels of TNF-α and IL-6 in the group with green tea extract supplement along with the training was reduced in comparison with the placebo and training group. This decrease was not statistically significant in terms of TNF-α, but it was significant for IL-6 factor. Conclusion: The results of the present study indicate that the use of green tea extract along with intense resistance training in athletes can reduce the production of some cytokines and thus reduce inflammatory injuries among them.

Keywords

References

1. Fiatarone-Singh MA. Exercise comes of age: rationale and recommendations for a geriatric exercise prescription. J Gerontol A Biol Sci Med Sci 2002; 57: M262- 82. 2. Ormsbee M, Ormsbee J, Thyfault E, Raymond M, Myung D, Robert C. Fat metabolism and acute resistance exercise in trained men. J Appl Physiol 2007; 102: 1767-72. 3. McGill SM, Cannon J, Andersen JT. Analysis of pushing exercises: Muscle activity and spine load while contrasting techniques on stable surfaces with a labile suspension strap training system. J Strength Cond Res 2014; 28: 105-16. 4. Gaedtke A, Morat T. TRX Suspension Training: A New Functional Training Approach for Older Adults - Development, Training Control and Feasibility. Int J Exerc Sci 2015; 8: 224-33. 5. Sadres E, Eliakim A, Constantini N, Lidor R, Falk B. The effect of long-term resistance training on anthropometric measures, muscle strength, and self concept in pre-pubertal boys. Pediatr Exerc Sci 2001; 13: 357-72. 6. Alessio HM, Hagerman AE, Fulkerson BK, Ambrose J, Rice RE, Wiley RL. Generation of reactive oxygen species after exhaustive aerobic and isometric exercise. Med Sci Sports Exerc 2000; 32: 1576-81. 7. Steinberg JG, Delliaux S, Jammes Y. Reliability of different blood indices to explore the oxidative stress in response to maximal cycling and static exercises. Clin Physiol Funct Imaging 2006; 26: 106-12. 8. Haddad JJ, Safieh-Garabedian B, Saade NE, Land SC. Thiol regulation of pro-inflammatory cytokines reveals a novel immunopharmacological potential of glutathione in the alveolar epithelium. J Pharmacol Exp Ther 2001; 296: 996-1005. 9. Kosmidou I, Vassilakopoulos T, Xagorari A, Zakynthinos S, Papapetropoulos A, Roussos C. Production of interleukin-6 by skeletal myotubes: role of reactive oxygen species. Am J Respir Cell Mol Biol 2002; 26: 587-93. 10. Kishimoto T. The biology of interleukin-6. Blood 1989; 74: 1-10. PMID:2473791 11. Fischer CP. Interleukin-6 in acute exercise and training: what is the biological relevance? Exerc Immunol Rev 2006; 12: 6-33. 12. Rahimi R. The Effect of Green Tea Extract on Expression of TNF-α After Resistance Exercise in Obese Men: Randomized, Double-Blind, Placebo-Controlled, Cross-Over Study. Iranian Journal of Nutrition Sciences & Food Technology 2017; 12 :9-18 ( Farsi). 13. Melgarejo E, Medina MA, Sanchez-Jimenez F, Urdiales JL. Targeting of histamine producing cells by EGCG: a green dart against inflammation? J Physiol Biochem 2010; 66: 265-70. 14. Banitalebi E, Razavi T, Norian M, Bagheri L. The effect of combined aerobic exercise training and green tea extract on serum TNF- α and IL- 6 levels in obese women with type 2 diabetes. D Med 2016; 23: 11- 20 (Farsi). 15. Tartibian B, Parse R, Baghaiee B. Effect of olive oil on IL-6, TNF-α and cortisol hormone levels in active girls after one session of an exhaustive exercise: a brief report. Tehran Univ Med J 2013; 71: 404-409. 16. Kosmidou I, Vassilakopoulos T, Xagorari A, Zakynthinos S, Papapetropoulos A, Roussos C. Production of interleukin-6 by skeletal myotubes: role of reactive oxygen species. Am J Respir Cell Mol Biol 2002; 26: 587-93. 17. Ohishi T, Goto S, Monira P, Isemura M, Nakamura Y. Anti-inflammatory Action of Green Tea. Antiinflamm Antiallergy Agents Med Chem 2016; 15: 74-90.
Journal of Military Medicine
Volume 23, Issue 1 - Serial Number 98
March and April 2021
Pages 69-74

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