Evaluation of the most common clinical signs and laboratory finidings of neonatal sepsis in in Baqyatallah and Najmie Hospitals from 1380 to 1384

Document Type : Original Research

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Abstract

Background. Sepsis is defined as systemic reactions against infection. Some risk factors of sepsis in infants are as follows: premature new born, PROM, maternal fever, chorioamnionitis, etc. Sepsis is categorized as early (within 7 days from birth) or late (day 8th to 28th) Objectives. In this study, the most common clinical manifestations and laboratory findings of sepsis in neonates and infants who were brought to Baqiyatalah hospital or Najmieh hospital between 1380 and 1384. Material and Methods. In this cross-sectional study, 140 neonates and infants were investigated with a mean age of 6.83 days ranging from 1 to 28 days. Results. According to this study, the prevalence of early sepsis was 85.6% and the most common manifestations were poor feeding (51.5%), lethargy (43.4%) and hyporeflexia (40.6%). Chief laboratory findings were positive blood culture (15.4%), positive CSF culture (2.2%), positive urine culture (13.3%), high ESR (7.9%), positive CRP (6.8%), neutropenia (2.9%), leucocytosis between 20,000 and 40,000 (2.1%), leucopenia (0.7%) and thrombocytopenia less than 100,000 (21%) which are in line with global statistics in most cases. Since sepsis is a major cause of infant mortality in the world, timely diagnosis and treatment as well as improving perinatal and infantile care can increase infants’ survival.

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Journal of Military Medicine
Volume 9, Issue 3 - Serial Number 29
September and October 2007
Pages 233-240

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