survivsl of stomach adenocarcinoma

Document Type : Original Research

Authors

Abstract

Bachground. In spite of decrease in burden of stomach cancer in the ‎developed world, the incidence of this disease is still high in the developing ‎countries including Iran. Due to the slow progression of the cancer within ‎stomach, the cancer is usually diagnosed in advanced stage leading to a high ‎mortality rate. The stomach cancer is the second cause of death due to ‎cancer after lung cancer. In this study, we studied the survival rate of ‎stomach cancer among patients hospitalized in Baghiatollah hospital in ‎Tehran, Iran between 2000 and 2005. ‎ Patients and Methods. In overall, we studied the survival rate of 209 ‎patients hospitalized for stomach cancer in Baghiatollah hospital. We used ‎patient files and abstracted demographic data as well as information about ‎stomach tumor, i.e. histopathology, stage of the disease. Crude survival rates ‎were studied by of stomach cancer using Kaplan-Meier and Life Table ‎methods. Cox regression model estimated the effect of demographic ‎information and tumor characteristics on death due to stomach cancer.‎ Results. we found a poor prognosis for our stomach cancer patients. More ‎than 20 percent of patients died of stomach cancer in the first three months ‎and only half of patients were still alive after nine months of follow-up. One, ‎three, and five years survival were 44, 19, and 11 percents, respectively. ‎Stage of tumor was the most important prognostic factor in this study, ‎although patients diagnosed with a stomach cancer staged IB, II, IIIA, and ‎IIIB had almost similar prognosis. Study of 13 patients with stomach ‎lymphoma showed a better survival rate compared to adenocarcinoma in ‎overall. ‎ Discussion. stomach cancer patients had a considerably poor prognosis in ‎Iran. Further studies are needed to improve the diagnostic and therapeutic ‎approached to improve the prognosis of these patients.

Keywords